Concurrent use of gallium nitrate with other potentially nephrotoxic drugs (eg, aminoglycosides, amphotericin B) may increase the risk for developing severe renal insufficiency in patients with cancer-related hypercalcemia. If use of a potentially nephrotoxic drug is indicated during gallium nitrate therapy, gallium nitrate administration should be discontinued and it is recommended that hydration be continued for several days after administration of the potentially nephrotoxic drug. Serum creatinine and urine output should be closely monitored during and subsequent to this period. Gallium nitrate therapy should be discontinued if the serum creatinine level exceeds 2.5 mg per dL .
Concurrent use with other potentially nephrotoxic drugs may increase the risk for developing severe renal insufficiency in patients with cancer-related hypercalcemia. If use of another potentially nephrotoxic drug is indicated during gallium nitrate therapy, discontinue gallium nitrate and continue hydration for several days after administration of the potentially nephrotoxic drug. Monitor renal function during and subsequent to this period. Discontinue gallium nitrate therapy if the serum creatinine level exceeds 2.5 mg/dL.
Commonly used brand name(s):
In the U.S.
Available Dosage Forms:
Therapeutic Class: Calcium Regulator
Gallium nitrate is used to treat hypercalcemia (too much calcium in the blood) that may occur with some types of cancer.
gallium nitrate is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For gallium nitrate, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to gallium nitrate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Studies on gallium nitrate have been done only in adult patients, and there is no specific information comparing use of gallium nitrate in children with use in other age groups.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of gallium nitrate in the elderly with use in other age groups, gallium nitrate is not expected to cause different side effects or problems in older people than it does in younger adults.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Using gallium nitrate with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using gallium nitrate with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using gallium nitrate with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
The presence of other medical problems may affect the use of gallium nitrate. Make sure you tell your doctor if you have any other medical problems, especially:
Make certain your health care professional knows if your diet includes large amounts of calcium-containing foods and/or vitamin D, such as milk or other dairy products. Also let your health care professional know if you are on any special diet, such as a low-sodium or a low-sugar diet.
The dose of gallium nitrate will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of gallium nitrate. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
It is important that your doctor check your progress at regular visits while you are receiving gallium nitrate. If your condition has improved and you are no longer receiving gallium nitrate, your progress must still be checked. The results of laboratory tests or the occurrence of certain symptoms will tell your doctor if your condition is coming back.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.More common
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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