Generic Name: griseofulvin (GRIS ee oh FUL vin)Brand Names: Fulvicin P/G, Fulvicin U/F, Grifulvin V, Gris-PEG, Grisactin 500, Grisactin Ultra
Griseofulvin is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.
Griseofulvin is used to treat fungal infections of the skin, hair, and nails such as jock itch, athlete's foot, and barber's itch.
Griseofulvin may also be used for purposes other than those listed in this medication guide.What is the most important information I should know about Grisactin 500 (griseofulvin)?Take all of the griseofulvin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Avoid prolonged exposure to sunlight. Griseofulvin increases sensitivity to sunlight, and severe burning may result.What should I discuss with my healthcare provider before taking Grisactin 500 (griseofulvin)?
You cannot take griseofulvin if you
have ever had an allergic reaction to it,
have porphyria, or
have liver disease.
Talk to your doctor before taking griseofulvin if you have any of the conditions listed above.Griseofulvin is in the FDA pregnancy category C. This means that it is not known whether griseofulvin will harm an unborn baby. In rare cases, the use of griseofulvin has been associated with conjoined twins. Do not take this medication without first talking to your doctor if you are pregnant. It is also not known whether griseofulvin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Griseofulvin may affect sperm and sperm production. It is recommended that you avoid fathering a child during treatment with griseofulvin and for 6 months following therapy.
Take griseofulvin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.Take each dose with a full glass (8 ounces) of water. Your doctor may recommend that you take griseofulvin with a fatty meal to increase its absorption into your body. Take all of the griseofulvin that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated. Shake the suspension well before measuring a dose. To ensure that you get a correct dose, measure the liquid form of griseofulvin with a dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
Store griseofulvin tablets, capsules, and suspension at room temperature away from moisture and heat.
Take the missed dose as soon as you remember. Take the rest of the day's doses at evenly spaced intervals unless your doctor directs otherwise.
Symptoms of a griseofulvin overdose are not well known but might include nausea, vomiting, diarrhea, headache, numbness and tingling, and confusion.
Other, less serious side effects may be more likely to occur. Continue to take griseofulvin and notify your doctor if you experience
white patches in your mouth (thrush/yeast infection);
nausea, vomiting, or diarrhea;
headache, dizziness, or tiredness;
numbness or tingling in your hands or feet; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Griseofulvin may decrease the effects of the following drugs:
oral anticoagulants (blood thinners) such as warfarin (Coumadin). A decrease in the effectiveness of anticoagulants could lead to blood clotting. It may be necessary to increase anticoagulant dosage.
salicylates such as aspirin, salsalate (Disalcid, Salsitab, Salflex, others), choline salicylate (Arthropan), magnesium salicylate (Doan's, Magan), and others. Larger doses of these medicines may be needed.
cyclosporine (Sandimmune, Neoral). Your doctor may need to adjust your cyclosporine dosage.
The effects of griseofulvin may be decreased by barbiturates such as phenobarbital (Luminal, Solfoton), pentobarbital (Nembutal), secobarbital (Seconal), amobarbital (Amytal), and butabarbital (Butisol). Larger doses of griseofulvin may be necessary if you are taking any of these drugs.
Drugs other than those listed here may also interact with griseofulvin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.