Drugs Information Online
Drugs and diseases reference index

Drugs and diseases reference index

Drugs A-Z List

Diseases & Conditions A-Z List

Herbs & Supplements

Medical Dictionary

Full Article

Popular Drugs

Popular Diseases & Conditions

Drugs reference index «Minocycline hydrochloride»

Minocycline hydrochloride

Brand names: Dynacin, Minocin

Why is Minocycline hydrochloride prescribed?

Minocin is a form of the antibiotic tetracycline.

It is given to help treat many different kinds of infection, including:

AcneAmebic dysenteryAnthraxCholeraGonorrhea (when penicillin cannot be given)PlagueRespiratory infections such as pneumoniaRocky Mountain spotted feverSyphilis (when penicillin cannot be given)Urinary tract infections, rectal infections, and infections of the cervix caused by certain microbes

Most important fact about Minocycline hydrochloride

To help clear up your infection completely, keep taking Minocin for the full time of treatment, even if you begin to feel better after a few days. Minocin, like other antibiotics, works best when there is a constant amount in the body. To help keep the level constant, take the doses at evenly spaced times around the clock.

It's important to take Minocin exactly as your doctor prescribes. Skipping doses or not completing the full dosage schedule may decrease the drug's effectiveness and increase the chances of bacterial resistance to Minocin and similar antibiotics.

How should you take Minocycline hydrochloride?

You should take Minocin at least 1 hour before or 2 hours after meals. Take Minocin exactly as directed. Your doctor will prescribe it for a specific number of days according to the type of infection being treated; keep taking the medication until you have used it all up.

To reduce the risk of throat irritation, take the capsule and tablet forms of Minocin with plenty of fluids. Swallow the pellet-filled capsules whole.

You should avoid use of antacids that contain aluminum, calcium, or magnesium, such as Maalox and Mylanta, and iron preparations such as ferrous sulfate. If you must take these medicines, take them 2 to 3 hours before or after taking Minocin.

  • If you miss a dose...Take it as soon as you remember, then space out evenly any remaining doses for that day. Never take 2 doses at the same time.
  • Storage instructions...Store capsules, tablets, or liquid at room temperature. Keep capsules and tablets away from moist places and direct light. Do not freeze the liquid.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Minocin.

  • Side effects may include:Altered liver function, blood disorders, diarrhea, difficulty swallowing, headache, inflammation of the colon or pancreas, loss of appetite, nausea, kidney problems, rash and other skin reactions, skin discoloration, tooth discoloration, vomiting

Why should Minocycline hydrochloride not be prescribed?

Do not take Minocin if you have ever had an allergic reaction to it or to any other tetracycline antibiotic.

Although Minocin may be given to kill meningococcal (spinal) bacteria in people who are carriers, it should not be given to treat actual meningococcal meningitis (inflammation in the spinal canal).

Minocin is not a first-choice drug for treating any staphylococcal ("staph") infection.

Special warnings about Minocycline hydrochloride

If you have a kidney problem, a normal dose of Minocin may amount to an overdose for you and could cause liver damage. Use caution if you have a liver condition. Expect a lower-than-average dosage if you have a kidney problem. If you need to take Minocin for an extended period of time, your doctor may order frequent blood tests to make sure you are not getting too much of the drug.

Because Minocin may make you dizzy or light-headed or cause a whirling feeling, do not drive, climb, or perform hazardous tasks until you know how the medication affects you.

Minocin should not be given to children 8 years old or younger, since it may cause discoloration of the teeth. Occasionally, Minocin has also caused tooth discoloration in adults.

Like other tetracycline antibiotics, Minocin may cause a sensitivity to light, and you may sunburn very easily. Be careful in sun and under sunlamps. If your skin turns red and hot, stop taking Minocin immediately.

While taking Minocin you may be especially susceptible to infections, including fungus infections such as vaginal yeast infection. If you do get an infection, check with your doctor immediately.

If you get a headache and blurry vision while taking Minocin, or if an infant receiving Minocin develops bulging of the "soft spots" (fontanels) on the head, this could mean that the drug is causing a buildup of fluid within the skull. It is important to stop taking Minocin and see a doctor immediately.

Minocin liquid contains a sulfite that can cause severe allergic reactions in susceptible people.

Possible food and drug interactions when taking Minocycline hydrochloride

If Minocin is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Minocin with the following:

Antacids containing aluminum, calcium, or magnesiumBlood thinners such as warfarinIron-containing preparations such as ferrous sulfateIsotretinoinOral contraceptivesPenicillin

Special information if you are pregnant or breastfeeding

If you are pregnant or plan to become pregnant, inform your doctor immediately. If you take Minocin during the second half of pregnancy, it may cause permanent yellow, gray, or brown discoloration of your baby's teeth.

There is reason to believe that taking Minocin during pregnancy could also harm the baby in other ways. Therefore, Minocin should be taken during pregnancy only as a last resort. Because Minocin appears in breast milk and could harm the baby, it should not be taken by a woman who is breastfeeding. If Minocycline hydrochloride is essential to your health, your doctor may advise you to discontinue breastfeeding until treatment is finished.

Recommended dosage for Minocycline hydrochloride


The usual dosage of Minocin is 200 milligrams to start with, followed by 100 milligrams every 12 hours. If you need to take more frequent doses, your doctor may prescribe two or four 50-milligram capsules initially, and then one 50-milligram capsule 4 times daily.

The dosage and the length of time you take the drug can vary according to your condition and the specific infection.


The usual dosage of Minocin is 4 milligrams per 2.2 pounds of body weight to start, followed by 2 milligrams per 2.2 pounds every 12 hours, up to the usual adult dose.


Any medication taken in excess can have serious consequences. If you suspect symptoms of an overdose of Minocin, seek medical attention immediately.

  • Symptoms of Minocin overdose may include:Dizziness, nausea, vomiting
  • Minocycline Prescribing Information (FDA)
  • Minocycline Professional Patient Advice (Wolters Kluwer)
  • Dynacin capsules Prescribing Information (FDA)
  • Dynacin MedFacts Consumer Leaflet (Wolters Kluwer)
  • Dynacin Prescribing Information (FDA)
  • Minocin MedFacts Consumer Leaflet (Wolters Kluwer)
  • Minocin Prescribing Information (FDA)
  • Minocycline Capsules Prescribing Information (FDA)
  • Solodyn Prescribing Information (FDA)
  • Solodyn Extended-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)
  • Solodyn Consumer Overview

Comment «Minocycline hydrochloride»