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Drugs reference index «Moxifloxacin Tablets»

Moxifloxacin Tablets


Moxifloxacin

Generic Name: Moxifloxacin (MOX-i-FLOX-a-sin)Brand Name: Avelox

Moxifloxacin are associated with an increased risk of tendon problems. These include pain, swelling, inflammation, and possible breakage of tendons. The risk of tendon problems is greater in patients who are over 60 years old, take corticosteroids (eg, prednisone), or have received kidney, heart, or lung transplants. The Achilles tendon in the back of the foot/ankle area is most often affected. However, problems may also occur in other tendons (eg, in the shoulder, arm, or hand). Problems may occur while you take Moxifloxacin or up to several months after you stop taking it.

Signs of tendon problems may include pain, soreness, redness, or swelling of a tendon or joint; bruising right after an injury in a tendon area; hearing or feeling a snap or pop in a joint or tendon area; or inability to move or bear weight on a joint or tendon area. Tell your doctor right away if you experience any of these symptoms while you take Moxifloxacin or within several months after you stop it.

Moxifloxacin are used for:

Treating infections caused by certain bacteria.

Moxifloxacin are a fluoroquinolone. It works by killing sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Do NOT use Moxifloxacin if:

  • you are allergic to any ingredient in Moxifloxacin or to any other quinolone antibiotic (eg, levofloxacin)
  • you have certain types of irregular heartbeat (eg, QT prolongation) or low blood potassium levels
  • you are taking cisapride, a class IA or III antiarrhythmic (eg, amiodarone, procainamide, quinidine, sotalol), astemizole, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Moxifloxacin:

Some medical conditions may interact with Moxifloxacin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a stomach infection, liver problems, brain or nervous system problems, muscle problems (eg, myasthenia gravis), increased pressure in the brain, Alzheimer disease, brain blood vessel problems, or a history of seizures
  • if you have a history of severe or persistent diarrhea, skin sensitivity to the sun, low blood potassium levels, heart problems (eg, fast or slow heartbeat, angina), irregular heartbeat (eg, QT prolongation), or heart attack, or if you have a family member with a history of irregular heartbeat
  • if you have a history of joint or tendon problems; rheumatoid arthritis; kidney problems or decreased kidney function; or heart, kidney, or lung transplant
  • if you take a corticosteroid (eg, prednisone) or participate in strenuous physical work or exercise

Some MEDICINES MAY INTERACT with Moxifloxacin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Corticosteroids (eg, prednisone) because the risk of tendon problems may be increased
  • Arsenic, astemizole, cisapride, class IA antiarrhythmics (eg, procainamide, quinidine), class IC antiarrhythmics (eg, flecainide, propafenone), class III antiarrhythmics (eg, amiodarone), diuretics (eg, furosemide, hydrochlorothiazide) dofetilide, droperidol, foscarnet, imidazoles (eg, ketoconazole), macrolides and ketolides (eg, erythromycin, azithromycin), nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), phenothiazines (eg, thioridazine), pimozide, procainamide, serotonin receptor antagonist antiemetics (eg, ondansetron), sotalol, terfenadine, tramadol, tricyclic antidepressants (eg, amitriptyline), warfarin, or ziprasidone because the actions and side effects of either medicine may be increased, possibly leading to abnormal heart rhythms
  • Risperidone because heart problems may occur
  • Live oral typhoid vaccine because its effectiveness may be decreased by Moxifloxacin

This may not be a complete list of all interactions that may occur. Ask your health care provider if Moxifloxacin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Moxifloxacin:

Use Moxifloxacin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Moxifloxacin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Moxifloxacin refilled.
  • Take Moxifloxacin by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Drink plenty of liquids while taking Moxifloxacin.
  • Do not take a product that has magnesium or aluminum, calcium, zinc, iron, or sucralfate in it within 8 hours before or 4 hours after you take Moxifloxacin. Examples of these products include antacids, multivitamins, buffered didanosine, didanosine suspension, and quinapril. Check with your doctor or pharmacist if you have a question about whether you should separate Moxifloxacin from a certain food or product.
  • Take Moxifloxacin on a regular schedule to get the most benefit from it.
  • To clear up your infection completely, take Moxifloxacin for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Moxifloxacin, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Moxifloxacin.

Important safety information:

  • Moxifloxacin may cause dizziness, drowsiness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Moxifloxacin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Be sure to use Moxifloxacin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Moxifloxacin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Moxifloxacin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Moxifloxacin only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Long-term or repeated use of Moxifloxacin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Moxifloxacin has infrequently caused tendon problems, including tendon rupture. If you experience any unusual pain or swelling in your joints (eg, shoulder, elbow, hand, hip, knee, ankle, foot), contact your doctor immediately. Rest and avoid exercise or other physically stressful activity until your doctor tells you otherwise.
  • Moxifloxacin may cause changes in certain heart tests (eg, electrocardiogram [ECG]). Be sure your doctor and lab personnel know you are using Moxifloxacin.
  • Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you use Moxifloxacin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Moxifloxacin with caution in the ELDERLY; they may be more sensitive to its effects (eg, tendon problems), especially if they take corticosteroids (eg, prednisone). They may also be more sensitive to other effects (eg, irregular heartbeat).
  • Moxifloxacin should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if Moxifloxacin can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Moxifloxacin while you are pregnant. It is not known if Moxifloxacin are found in breast milk. Do not breast-feed while taking Moxifloxacin.

Possible side effects of Moxifloxacin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; nausea; trouble sleeping; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or tarry stools; burning, numbness, tingling, pain, or weakness of the arms, hands, legs, or feet; chest pain; dark urine; decreased urination; fainting; fever, chills, or unusual cough; hallucinations; inability to move or bear weight on a joint or tendon area; irregular heartbeat; joint pain; moderate to severe sunburn; mood or mental changes (eg, new or worsening anxiety, agitation, confusion depression, nervousness, restlessness, sleeplessness); muscle pain or weakness; pain, soreness, redness, swelling, weakness, or bruising of a tendon or joint area; pale stools; persistent sore throat; pounding in the chest; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea; severe or persistent dizziness; shortness of breath; stomach pain/cramps; suicidal thoughts or actions; tremor; unusual bruising or bleeding; unusual tiredness or weakness; vaginal yeast infection; vision changes; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include dizziness; drowsiness; facial swelling or numbness; hot and cold flushes; mild to moderate disorientation; nausea; slurring of speech.

Proper storage of Moxifloxacin:

Store Moxifloxacin at 77 degrees F (25 degrees C) in a tightly closed container. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not refrigerate. Do not store in the bathroom. Keep Moxifloxacin out of the reach of children and away from pets.

General information:

  • If you have any questions about Moxifloxacin, please talk with your doctor, pharmacist, or other health care provider.
  • Moxifloxacin are to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Moxifloxacin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • moxifloxacin Advanced Consumer (Micromedex) - Includes Dosage Information
  • Avelox Prescribing Information (FDA)
  • Avelox Detailed Consumer Information (PDR)
  • Avelox Consumer Overview
  • Avelox I.V. Advanced Consumer (Micromedex) - Includes Dosage Information

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