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Drugs reference index «regadenoson Intravenous»

regadenoson (Intravenous route)


Commonly used brand name(s):

In the U.S.

  • Lexiscan

Available Dosage Forms:

  • Solution

Therapeutic Class: Diagnostic Agent, Cardiac Function

Pharmacologic Class: Adenosine A2a Receptor Agonist

Uses For regadenoson

Regadenoson is used as a pharmacologic stress agent for radionuclide myocardial perfusion imaging (MPI) in patients unable to undergo adequate exercise stress .

regadenoson is available only with your doctor's prescription .

Before Using regadenoson

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For regadenoson, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to regadenoson or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Appropriate studies have not been performed on the relationship of age to the effects of regadenoson in the pediatric population. Safety and efficacy have not been established .


Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of regadenoson in the elderly. However, elderly patients are more likely to have low blood pressure, which may require caution in patients receiving regadenoson .


Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of regadenoson. Make sure you tell your doctor if you have any other medical problems, especially:

  • Heart block, second or third degree (type of abnormal heart rhythm) or
  • Sinus node dysfunction (type of abnormal heart rhythm)—Should not use in these conditions unless patients have a pacemaker that works .
  • Breathing problems or lung disease (e.g., asthma or COPD) or
  • Ischemia or
  • Low blood pressure (hypotension)—Use with caution. May make these conditions worse .

Proper Use of regadenoson

A nurse or other trained health professional will give you regadenoson. regadenoson is given through a needle placed into one of your veins .

Precautions While Using regadenoson

Tell your doctor right away if you start having chest pain, trouble with breathing, lightheadedness, or if you feel faint after regadenoson is injected. You may be having a serious side effect from regadenoson .

Make sure your doctor knows if you are using theophylline (e.g., Theo-24®, Uniphyl®) before you receive regadenoson. You may need to stop using theophylline for at least twelve hours before the test .

Do not take anything that contains caffeine for at least twelve hours before you receive regadenoson. This includes medicines, foods, and beverages with caffeine, such as coffee, tea, and cola drinks .

regadenoson Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common
  • Arm, back, or jaw pain
  • chest pain or discomfort
  • difficult or labored breathing
  • fast or irregular heartbeat
  • nausea
  • shortness of breath
  • sweating
  • tightness in chest
  • wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

  • Increased heart rate
  • dizziness
  • feeling of warmth
  • redness of the face, neck, arms and occasionally, upper chest

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Change in taste
  • headache
  • loss of taste
  • stomach soreness or discomfort

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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