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Drugs reference index «Silodosin»


Generic Name: Silodosin (sil-OH-doe-sin)Brand Name: Rapaflo

Silodosin is used for:

Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).

Silodosin is an alpha-blocker. It works by relaxing muscles in the prostate and bladder, which helps to improve urine flow and reduce symptoms of BPH.

Do NOT use Silodosin if:

  • you are allergic to any ingredient in Silodosin
  • you have severe kidney or liver problems
  • you are taking ketoconazole, clarithromycin, itraconazole, nefazodone, or ritonavir
  • you are taking another alpha-blocker (eg, prazosin)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Silodosin :

Some medical conditions may interact with Silodosin . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of blood pressure problems and you are taking blood pressure medication
  • if you have a history of prostate cancer
  • if you have kidney or liver problems
  • if you will be having eye surgery (eg, cataract surgery)

Some MEDICINES MAY INTERACT with Silodosin . Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Alpha-blockers (eg, prazosin) or phosphodiesterase inhibitors (eg, sildenafil) because symptoms of low blood pressure (eg, severe dizziness, lightheadedness, and fainting) may occur
  • Azole antifungals (eg, itraconazole, ketoconazole), clarithromycin, cyclosporine, diltiazem, erythromycin, fluconazole, nefazodone, probenecid, ritonavir, valproic acid, or verapamil because they may increase the risk of Silodosin 's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Silodosin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Silodosin :

Use Silodosin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Silodosin . Talk to your pharmacist if you have questions about this information.
  • Take Silodosin by mouth with a meal.
  • If you miss a dose of Silodosin , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If you miss more than 2 dose of Silodosin , contact your doctor for instructions.

Ask your health care provider any questions you may have about how to use Silodosin .

Important safety information:

  • Silodosin may cause drowsiness, dizziness, lightheadedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Silodosin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Silodosin may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Do not drive or perform other possibly unsafe tasks for 12 hours after your first dose of Silodosin or after any dose increase.
  • Tell your doctor or dentist that you take Silodosin before you receive any medical or dental care, emergency care, or surgery.
  • Silodosin may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
  • Lab tests, including kidney or liver function, may be performed while you use Silodosin . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Silodosin should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: It is not known if Silodosin can cause harm to the fetus. It is not known if Silodosin is found in breast milk. Silodosin is not approved for use in women.

Possible side effects of Silodosin :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Decreased sexual ability; diarrhea; dizziness; headache; lightheadedness; runny or stuffy nose; sinus inflammation; stomach pain; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine; fainting; irregular heartbeat; prolonged, painful erection; severe of persistent dizziness; unusual bruising; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include fainting; severe or persistent dizziness or lightheadedness.

Proper storage of Silodosin :

Store Silodosin at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Silodosin out of the reach of children and away from pets.

General information:

  • If you have any questions about Silodosin , please talk with your doctor, pharmacist, or other health care provider.
  • Silodosin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Silodosin . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Silodosin Professional Patient Advice (Wolters Kluwer)
  • silodosin Advanced Consumer (Micromedex) - Includes Dosage Information
  • Rapaflo Prescribing Information (FDA)
  • Rapaflo Consumer Overview

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