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Drugs reference index «Singulair»



Generic name: Montelukast sodiumBrand names: Singulair

What is Singulair?

Singulair is a medicine called a leukotriene receptor antagonist. It works by blocking substances in the body called leukotrienes. Blocking leukotrienes improves asthma and allergic rhinitis.

Singulair is prescribed for the treatment of asthma, the prevention of exercise-induced asthma, and allergic rhinitis (sneezing, stuffy nose, runny nose, itching of the nose, and outdoor and indoor allergies).

What is the most important information I should know about Singulair?

Singulair alleviates the on-going symptoms of asthma, but it won't stop an acute asthma attack.

If you have difficulty breathing while taking Singulair, or find that you need your orally inhaled bronchodilator more often than usual (or require more puffs than prescribed), notify your doctor.

If your asthma gets worse after exercise, continue using a short-acting inhaled airway opener to prevent the problem and relieve attacks.

Who should not take Singulair?

Do not take Singulair if you are allergic to any of its ingredients.

What should I tell my doctor before I take the first dose of Singulair?

Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Singulair. Also, talk to your doctor about your complete medical history, especially if you have phenylketonuria (an inability to process phenylalanine).

What is the usual dosage?

The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.


Adults and children ≥15 years: The usual dose is one 10 milligram (mg) tablet once a day in the evening.

Children 6 to 14 years: The usual dose is one 5 mg chewable tablet once a day in the evening.

Children 2 to 5 years: The dosage is one 4 mg chewable tablet or 1 packet of 4 mg oral granules per day, taken in the evening.

Children 12 to 23 months: The dosage is 1 packet of 4 mg oral granules taken once a day in the evening.

The safety and effectiveness of Singulair for treating asthma in children <12 months have not been studied.

Seasonal Allergies in Adults and Children ≥2 years and Perennial (year-round) Allergies in Adults and Children ≥6 months

Adults and children ≥15 years: The usual dose is one 10 mg tablet once a day taken at any time.

Children 6 to 14 years: The usual dose is one 5 mg chewable tablet once a day taken at any time.

Children 2 to 5 years: The dosage is one 4 mg chewable tablet or 1 packet of 4 mg oral granules per day, taken at any time.

Children 6 to 23 months: The dosage is 1 packet of 4 mg oral granules per day, taken at any time.

Exercise-Induced Bronchoconstriction

Adults and children ≥15 years: The usual dose is one 10 mg tablet taken at least 2 hours before exercise. However, if you are already taking one tablet daily for your asthma or allergies, you do not need to take a second one before exercising. An additional dose should not be taken within 24 hours of a previous dose.

How should I take Singulair?

Take a Singulair tablet once daily, whether or not you have any symptoms. The tablet can be taken with or without food. If you have asthma, or asthma and allergies, take Singulair in the evening. If you have only allergies, you can take Singulair at any time.

For administration to children, place the oral granules directly in the child's mouth. The granules may also be mixed with a spoonful of one of the following soft foods: applesauce, carrots, rice, or ice cream. The food should be cold or at room temperature.

The granules can also be dissolved in 1 teaspoonful (5 milliliters) of cold or room temperature baby formula or breast milk. You should not use any other liquid to dissolve the granules. However, the child can drink liquids after the granules have been swallowed. Do not open the granules packet until your child is ready to take them. Once the packet is opened, give the full dose of medication within 15 minutes. Throw away any unused portion of the granules; do not store them for future use.

What should I avoid while taking Singulair?

If you have asthma and if your asthma is made worse by aspirin, continue to avoid aspirin or other medicines called nonsteroidal anti-inflammatory drugs while taking Singulair.

What are possible food and drug interactions associated with Singulair?

If Singulair is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Singulair with phenobarbital or rifampin.

What are the possible side effects of Singulair?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Singulair.

Side effects may include: abdominal pain, abnormal dreams, allergic reaction, bronchitis, bruising, cough, dental pain, depression, diarrhea, difficulty breathing or swallowing, dizziness, drowsiness, ear infection, ear pain, eczema, eye inflammation, fatigue, feeling anxious, fever, flu, hallucinations, headache, hives, indigestion and other digestive problems, infection, insomnia, irritability, itching, joint pain, laryngitis, leg pain, muscle aches and cramps, nasal congestion, nausea, pancreatitis, pins and needles/numbness, pneumonia, rash, restlessness, runny nose, seizures, sinus pain, skin inflammation, sneezing, sore throat, suicidal thoughts and actions (including suicide), swelling due to fluid retention, swelling of the mouth or throat, upper respiratory infection, tendency to bleed easily, thirst, tremor, viral infection, vomiting

Can I receive Singulair if I am pregnant or breastfeeding?

The effects of Singulair during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.

What should I do if I miss a dose of Singulair?

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

How should I store Singulair?

Store at room temperature, away from moisture and light.

  • Singulair Prescribing Information (FDA)
  • Singulair Advanced Consumer (Micromedex) - Includes Dosage Information
  • Singulair MedFacts Consumer Leaflet (Wolters Kluwer)
  • Singulair Consumer Overview

See Also...

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