Trade Names:Eye-Sed- Solution 0.25%
Trade Names:Orazinc- Tablets 110 mg (25 mg zinc)- Capsules 220 mg (50 mg zinc)
Trade Names:Verazinc- Capsules 220 mg (50 mg zinc)
Trade Names:Zinc 15- Tablets 66 mg (15 mg zinc)
Trade Names:Zinc-220- Capsules 220 mg (50 mg zinc)
Trade Names:Zinca-Pak- Injection 1 mg/ml (as sulfate [as 4.39 mg heptahydrate or 2.46 mg anhydrous])- Injection 5 mg/ml (as 21.95 mg sulfate)
Trade Names:Zincate- Capsules 220 mg (50 mg zinc)Rivasol (Canada)
Acts as integral part of several enzymes important to protein and carbohydrate metabolism, wound healing, maintenance of normal growth and skin hydration, and senses of taste and smell.
Some studies indicate that ingestion with certain foods may inhibit zinc absorption. It is poorly absorbed from the GI tract (only 20% to 30%).
Major stores of zinc are in the skeletal muscle and bone.
About 90% is excreted through the intestines; about 2% in the urine.
Dietary supplementation; supplement to IV solutions given for TPN; treatment or prevention of zinc deficiencies. Ophthalmic solution used as mild astringent for relief of eye irritation.
Treatment of acrodermatitis enteropathica and delayed wound healing associated with zinc deficiency; treatment of acne, rheumatoid arthritis, Wilson's disease.
Direct injection of undiluted solution into peripheral vein.
PO 25 to 50 mg/day.Supplement to IV SolutionsMetabolically stable adults
IV 2.5 to 4 mg/day. Add 2 mg/day for acute catabolic state.Stable adults with fluid loss from small bowel
IV Increase dose by 12.2 mg/L TPN or 17.1 mg/kg loose stool or ileostomy output.Full-term infants and children under 5 yr
IV 100 mcg/kg/day.Premature infants under 3 kg
IV 300 mcg/kg/day.AstringentAdults
Ophthalmic 1 to 2 gtt into eye(s) up to 4 times daily.
Absorption of these agents may be decreased.
None well documented.
Nausea; vomiting (especially in large oral doses).
Category C . Routine supplementation during pregnancy is not recommended.
Excreted in breast milk.
Dosage reduction may be required in patients with renal dysfunction.
In healthy people may be harmful.
Some of these products contain benzyl alcohol, which has been associated with a fatal “gasping” syndrome in premature infants.
Some contain benzyl alcohol, which is associated with fatal “gasping” syndrome in infants.
Nausea, vomiting, dehydration, restlessness, sideroblastic anemia, profuse sweating, hyperamylasemia.
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