Generic Name: demeclocycline (DEM e kloe SYE kleen)Brand Names: Declomycin
Demeclocycline is a tetracycline antibiotic. It fights bacteria in the body.
Demeclocycline is used to treat many different bacterial infections, such as urinary tract infections, acne, gonorrhea, chlamydia, and others.
Demeclocycline may also be used for other purposes not listed in this medication guide.
If you are using demeclocycline to treat gonorrhea, your doctor may test you to make sure you do not also have syphilis, another sexually transmitted disease.FDA pregnancy category D. This medication can cause harm to an unborn baby, including permanent discoloration of the teeth later in life. Do not use demeclocycline without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Demeclocycline can make birth control pills less effective. Use a non-hormonal method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while you are taking demeclocycline. Demeclocycline passes into breast milk and may affect bone and tooth development in a nursing infant. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. Children younger than 8 years old should not take demeclocycline. Demeclocycline can cause permanent tooth discoloration and can also affect a child's growth.
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.
Take demeclocycline with a full glass of water (8 ounces).Take this medication on an empty stomach, at least 1 hour before or 2 hours after meals.
Do not take demeclocycline with milk or other dairy products, unless your doctor has told you to. Dairy products can make it harder for your body to absorb the medicine.Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Demeclocycline will not treat a viral infection such as the common cold or flu. Do not give this medicine to another person, even if they have the same condition you have.
If you need to have any type of surgery, tell the surgeon ahead of time that you are taking demeclocycline. You may need to stop using the medicine for a short time.Throw away any unused demeclocycline when it expires or when it is no longer needed. Do not take any demeclocycline after the expiration date printed on the label. Using expired demeclocycline can cause damage to your kidneys. Store this medication at room temperature away from moisture and heat.
See also: Demeclocycline dosage in more detail
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Avoid taking this medicine just before lying down. It may cause heartburn or ulcers in your esophagus (food pipe).Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Demeclocycline can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun. Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking demeclocycline.
severe headache, dizziness, blurred vision;
fever, chills, body aches, flu symptoms;
severe blistering, peeling, and red skin rash;
urinating less than usual or not at all;
pale or yellowed skin, dark colored urine, fever, confusion or weakness;
severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate;
loss of appetite, jaundice (yellowing of the skin or eyes); or
easy bruising or bleeding, unusual weakness.
Less serious side effects may include:
sores or swelling in your rectal or genital area;
mild nausea, vomiting, diarrhea, or stomach upset;
white patches or sores inside your mouth or on your lips;
swollen tongue, trouble swallowing; or
vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for SIADH:
Initial dose: 300 mg orally 4 times a day.Maintenance dose: 300 to 900 mg/day orally or the lowest effective dosage to prevent hyponatremia.
Before taking demeclocycline, tell your doctor if you are taking any of the following drugs:
cholesterol-lowering medications such as cholestyramine (Prevalite, Questran) or colestipol (Colestid);
tretinoin (Renova, Retin-A, Vesanoid);
an antacid such as Tums, Rolaids, Milk of Magnesia, Maalox, and others;
a product that contains bismuth subsalicylate such as Pepto-Bismol;
minerals such as iron, zinc, calcium, magnesium, and over-the-counter vitamin and mineral supplements;
a blood thinner such as warfarin (Coumadin); or
a penicillin antibiotic such as amoxicillin (Amoxil, Trimox, others), penicillin (BeePen-VK, Pen-Vee K, Veetids, others), dicloxacillin (Dynapen), oxacillin (Bactocill), and others.
This list is not complete and there may be other drugs that can interact with demeclocycline. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.