Medical Dictionary Definitions A-Z List
Medical Dictionary Definitions A - Z - «G»:
Gene, housekeeping: See: Housekeeping gene....
A detectable genetic trait or segment of DNA that can be identified and tracked. A marker gene can serve as a flag for another gene, sometimes called the target gene. A marker gene must be on the same chromosome as the target gene and near enough to it so that the two genes (the marker...
Gene, Med1 DNA repair
Gene, Med1 DNA repair: A gene that codes for one of the key enzymes involved in repairing DNA. The DNA in genes is constantly mutating and being repaired. This repair process is controlled by special genes. A mutation in a DNA repair gene such as Med1 can cripple the repair process and cause a casca...
A gene that regulates the expression
of other genes. A regulatory gene is a nosy gene whose prime preoccupation is to horn in
on other genes and control the rate at which they make products....
Gene, suicide: A gene whose expression in a cell is lethal for that cell.
Suicide genes form the basis of a strategy for making cancer cells more vulnerable, more sensitive to chemotherapy. The approach has been to attach parts of genes expressed in cancer cells to other genes for enzymes not found...
Gene, transporter: A gene that allows drugs to enter
cells or, in some cases, acts to keep them out. Transporter genes may account for discrepancies in the way drugs such as antidepressants, anticonvulsants, and chemotherapy agents work in different people. Also known as a drug-transporter gene....
Gene, Y-linked: A gene on the Y chromosome.
(Y-linkage is analogous to X-linkage (the presence of a gene on the X chromosome) in that it says a gene is on one of the sex chromosomes.)
It has often been said that little is known about genes that may be Y-linked. This is no longer true. As of the yea...
Gene, zygotic lethal
Gene, zygotic lethal: A gene that is lethal (fatal) for the zygote, the cell formed by the union of a sperm (male sex cell) and an ovum (female sex cell). The zygote would normally develop into an embryo, as instructed by the genetic material within the unified cell. However, a zygotic lethal gene ...
Gene-expression profiling: A genomic technique that based on the fact that only a fraction of the genes encoded in the genome of a cell are expressed by being transcribed into messenger RNA (mRNA). The complement of mRNAs in a cell largely dictates its complement of proteins. Consequently, gene expr...
General Clinical Research Center
General Clinical Research Center: (Abbreviated GCRC). See: Clinical Research Center....
General paresis: Progressive dementia and
generalized paralysis due to chronic inflammation of the covering and
substance of the brain (meningoencephalitis). General paresis is a
part of late (tertiary) syphilis, occurring a decade or more after
the initial infection....
Generalized anxiety disorder
Generalized anxiety disorder: Abbreviated GAD. A condition characterized by 6 months or more of chronic, exaggerated worry and tension that is unfounded or much more severe than the normal anxiety most people experience. People with GAD usually expect the worst. They worry excessively about money, h...
Generalized tonic-clonic seizure
Generalized tonic-clonic seizure: See: Grand mal....
Generic: 1. The chemical name of a drug.
2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold.
3.A term referring to any drug marketed under its
chemical name without advertising.
Generic drugs marketed without brand names a...
Generic drug: The term "generic" has several meanings as regards drugs:
The chemical name of a drug.
A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug is sold.
A term referring to any drug marketed under its
chemical name without ...