Medical Dictionary Definitions A-Z List
Medical Dictionary Definitions A - Z - «S»:
Septum, ventricular: The wall between the two lower chambers (the
right and left ventricles) of the heart....
Sequela: A pathological
condition resulting from a prior disease, injury, or attack. As for example,
a sequela of polio. Verbatim from the Latin "sequela" (meaning sequel). Plural: sequelae....
Sequelae: See: Sequela....
Sequence tagged site (STS)
Sequence tagged site (STS): A short (200 to 500 base
pair) DNA sequence that occurs but once in the genome and whose location and base
sequence are known.
STSs are detectable by polymerase chain reaction (PCR), are useful for
localizing and orienting the mapping and sequence data, and serve as land...
Sequence, complementary: Nucleic acid sequence of bases
that can form a double- stranded structure by matching base pairs. For example, the
complementary sequence to C-A-T-G (where each letter stands for one of the bases in DNA)
Sequence, conserved: A base sequence in a DNA molecule
(or an amino acid sequence in a protein) that has remained essentially unchanged
Sequence, draft DNA
Sequence, draft DNA: Sequence of a DNA with less accuracy than a finished sequence. In a draft sequence, some segments are missing or are in the wrong order or are oriented incorrectly. A draft sequence is as opposed to a finished DNA sequence....
Sequence, finished DNA
Sequence, finished DNA: A DNA sequence in which the bases are identified to an accuracy of no more than 1 error in 10,000 and are placed in the right order and orientation along a chromosome with almost no gaps. A finished sequence is as opposed to a draft DNA sequence....
Sequence, intervening: An intervening sequence is the part of a gene that is initially transcribed from the DNA into RNA (specifically, into the primary RNA transcript) but then is excised (removed) from it when the so-called exxon sequences on either side of it are spliced together.
Sequence, Klippel-Feil: See: Klippel-Feil sequence....
Sequence, regulatory: A sequence of bases in DNA that
controls gene expression....
Sequencing: Learning the order of nucleotides (base
sequences) in a DNA or RNA molecule or the order of amino acids in a protein.
In the case of DNA sequencing, the precise ordering of the bases (A,T,G,C) from which the DNA is composed is determined....
Sequester: 1. In medicine, to set apart, detach or separate a small portion of tissue from the rest.
2. In bone, for a piece of dead bone to separate from the sound bone.
3. In biochemistry, to isolate a constituent of a system by chelation or other means.
From the French sequestrer, from the late...
Ser: Serine. See also: Amino acid symbols....
Serendipity: An accidental and fortunate discovery. Not all good medical research by any means is done by design. Some is by serendipity, pure good luck.
A celebrated instance of serendipity in biomedical research took place in 1928 at St Mary's Hospital in London. While studying staphylococci (sta...