Tandem mass spectrometry: An instrument used in medical laboratories consisting of two mass spectrometers in series connected by a chamber known as a collision cell. The sample to be examined is essentially sorted and weighed in the first mass spectrometer, then broken into pieces in the collision cell, and a piece or pieces sorted and weighed in the second mass spectrometer. Tandem mass spectrometry is used in newborn screening to detect molecules such as amino acids (the building blocks of proteins) and fatty acids. Tandem mass spectrometry may be abbreviated as Tandem MS or MS/MS. See also: Mass spectrometry.
What is tandem mass spectrometry? Tandem mass spectrometry (MS/MS) is perhaps the most significant advance in newborn screening in the past 30 years.
Using Tandem Mass Spectrometry for Metabolic Disease Screening Among Newborns A Report of a Work Group. The following CDC staff members prepared this report:
Tandem mass spectrometry purposely produces fragment ions post-source and can drastically change the sort of data achieved by an experiment. By understanding the origin of ...
Peptide sequencing by tandem mass spectrometry - an MS-MS daughter or product ion spectrum. A protein identification study would proceed as follows:
Tandem mass spectrometry: An instrument used in medical laboratories consisting of two mass spectrometers in series connected by a chamber known as a collision cell.