Vaginismus: A painful spasm and contraction of the muscles of the vagina that prevents sexual intercourse. The condition results in pain when vaginal sexual intercourse is attempted or, in some cases, during a pelvic examination by a health-care provider. Vaginismus is not common, and its cause is poorly understood. Anxiety, past sexual trauma, or other psychological conditions have been suggested as potential contributing factors. Vaginismus is considered to be a form of female sexual dysfunction. Treatment of vaginismus involves education, counseling, and the use of vaginal dilation exercises.