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Drugs reference index «Penciclovir»



Brand names: Denavir

Why is Penciclovir prescribed?

Denavir cream is used to treat recurrent cold sores on the lips and face. It works by interfering with the growth of the herpesvirus responsible for the sores.

Most important fact about Penciclovir

You should begin applying Denavir at the first hint of a developing cold sore. The drug will not cure herpes, but it will reduce pain and may speed healing.

Check with your doctor if your cold sore does not improve or becomes worse. You could have an infection.

How should you take Penciclovir?

Avoid using Denavir cream in or near the eyes; it can irritate them. Apply it only to sores on the lips and face.

  • If you miss a dose...Apply it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule.
  • Storage instructions...Store at room temperature; avoid freezing.

What side effects may occur?

Reactions to Denavir are quite rare. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Penciclovir.

  • Side effects may include:Headache, hives, itching, numbing of the skin, pain, rash, skin discoloration, skin reaction or swelling where the cream was applied, swelling in the mouth and throat, taste or smell alteration, tingling, worsened condition

Why should Penciclovir not be prescribed?

If you have ever had an allergic reaction to any of the ingredients in Denavir, you should not use Penciclovir.

Special warnings about Penciclovir

It is not known whether Denavir is effective for people with weak immune systems.

Possible food and drug interactions when taking Penciclovir

No interactions with Denavir cream have been reported.

Special information if you are pregnant or breastfeeding

The effects of Denavir during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Researchers do not know whether Penciclovir will appear in breast milk after external application. For safety's sake, your doctor may advise you to discontinue breastfeeding your baby until your treatment with Denavir is finished.

Recommended dosage for Penciclovir


Apply cream every 2 hours, while awake, for 4 days.

The safety and effectiveness of Penciclovir in children less than 12 years old have not been established.


There have been no reported overdoses of Penciclovir. Even if the cream is accidentally swallowed, it is unlikely to cause a harmful reaction.

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