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Synagis
Synagis


Synagis

Generic Name: Palivizumab (pal-i-VIZ-u-mab)Brand Name: Synagis

Synagis is used for:

Preventing serious lower respiratory tract infection caused by respiratory syncytial virus (RSV) in children at high risk of RSV disease.

Synagis is a monoclonal antibody. It works by preventing RSV from reproducing.

Do NOT use Synagis if:

  • you are allergic to any ingredient in Synagis

Contact your doctor or health care provider right away if any of these apply to you.

Before using Synagis :

Some medical conditions may interact with Synagis . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a bleeding or blood clotting disorder or low blood platelet levels
  • if you are having heart surgery (cardiopulmonary bypass)
  • if you are taking a blood thinner (eg, warfarin)

Some MEDICINES MAY INTERACT with Synagis . However, no specific interactions with Synagis are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Synagis may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Synagis :

Use Synagis as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Synagis . Talk to your pharmacist if you have questions about this information.
  • Synagis is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Synagis at home, a health care provider will teach you how to use it. Be sure you understand how to use Synagis . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Synagis if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Continue to use Synagis even if you feel well. Do not miss any doses.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Synagis , contact your doctor right away.

Ask your health care provider any questions you may have about how to use Synagis .

Important safety information:

  • Children, including those who develop RSV, should continue to receive monthly doses of Synagis throughout the RSV season (generally November through April in the Northern Hemisphere). The first dose should be given before the RSV season begins.
  • PREGNANCY and BREAST-FEEDING: Synagis is not for use in adults. It is not known if Synagis can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Synagis while you are pregnant. Synagis is not indicated for use in breast-feeding mothers. Do not breast-feed while taking Synagis .

Possible side effects of Synagis :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Cough; diarrhea; mild fever; minor pain, redness, swelling, or warmth at the injection site; runny or stuffy nose; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness; muscle weakness or limpness); blue lips or skin (including under the fingernails); ear pain or discharge; fever; irregular heartbeat; stomach pain; unusual bruising or bleeding; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately.

Proper storage of Synagis :

Synagis is usually handled and stored by a health care provider. If you are using Synagis at home, store Synagis as directed by your pharmacist or health care provider. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Synagis out of the reach of children and away from pets.

General information:

  • If you have any questions about Synagis , please talk with your doctor, pharmacist, or other health care provider.
  • Synagis is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Synagis . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

  • Synagis Prescribing Information (FDA)
  • Synagis Advanced Consumer (Micromedex) - Includes Dosage Information
  • Synagis Consumer Overview
  • Palivizumab Professional Patient Advice (Wolters Kluwer)

See Also...

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