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Drugs reference index «Efavirenz, Emtricitabine, Tenofovir»

Efavirenz, Emtricitabine, Tenofovir

Brand names: Atripla

Why is Efavirenz, Emtricitabine, Tenofovir prescribed?

Atripla is a combination drug that contains three anti-HIV medications. It is used to help stop HIV replication in the body and also to raise T-cell levels. Atripla does not cure HIV or AIDS.

Most important fact about Efavirenz, Emtricitabine, Tenofovir

Some people who have taken medicine like Atripla (which contains nucleoside analogs) have developed a serious condition called lactic acidosis (build up of an acid in the blood). Lactic acidosis can be a medical emergency and may need to be treated in the hospital.

Some people who have taken medicines like Atripla have developed serious liver problems called hepatotoxicity, with liver enlargement (hepatomegaly) and fat in the liver (steatosis).

How should you take Efavirenz, Emtricitabine, Tenofovir?

Atripla should be taken on an empty stomach. Your dosage could be taken at bedtime to make some side effects less bothersome

  • If you miss a dose...Do not miss a dose of Atripla. If you forget to take Atripla, take the missed dose right away, unless it is almost time for your next dose. Do not double the next dose. Carry on with your regular dosing schedule. If you need help in planning the best times to take your medicine, ask your doctor or pharmacist.
  • Storage instructions...Store at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Efavirenz, Emtricitabine, Tenofovir.

  • Side effects may include:Diarrhea, dizziness, drowsiness, gas, headache. rash, tiredness, trouble concentrating, trouble sleeping, unusual dreams, upset stomach, vomiting

Why should Efavirenz, Emtricitabine, Tenofovir not be prescribed?

Do not take Atripla if you are allergic to it or any of its ingredients. The active ingredients of Atripla are efavirenz, emtricitabine, and tenofovir.

Special warnings about Efavirenz, Emtricitabine, Tenofovir

Do not get pregnant or breastfeed while taking Atripla. If you do become pregnant, contact your doctor right away. Also, take the necessary precautions while having sexual contact to avoid infecting others with HIV/AIDS.

Tell your doctor what prescription, over-the-counter, and herbal medications you are taking before beginning therapy with Atripla. Also, talk to your doctor about your complete medical history. If you have/had seizures, or bone, liver (including Hepatitis B), or kidney problems, tell your doctor. Your doctor should also know if you are pregnant, plan to become pregnant, or nursing.

Possible food and drug interactions when taking Efavirenz, Emtricitabine, Tenofovir

If Atripla is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Atripla with the following:

EmtricitabineLamivudineSt. John's wort

Special information if you are pregnant or breastfeeding

Do not begin treatment with Atripla if you are pregnant, planning to become pregnant, or are nursing. Atripla is hazardous to an unborn baby if taken within the first trimester of development. This drug will pass through your breast milk; therefore do not breastfeed while being treated with Atripla.

Recommended dosage for Efavirenz, Emtricitabine, Tenofovir


The usual adult dosage of Atripla is one tablet once per day. Atripla should not be used in children under the age of 18.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

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