Insulin resistance: The diminished ability of cells to respond to the action of insulin in transporting glucose (sugar) from the bloodstream into muscle and other tissues. Insulin resistance typically develops with obesity and heralds the onset of type 2 diabetes. It is as if insulin is "knocking" on the door of muscle. The muscle hears the knock, opens up, and lets glucose in. But with insulin resistance, the muscle cannot hear the knocking of the insulin (the muscle is "resistant"). The pancreas makes more insulin, which increases insulin levels in the blood and causes a louder "knock." Eventually, the pancreas produces far more insulin than normal and the muscles continue to be resistant to the knock. As long as one can produce enough insulin to overcome this resistance, blood glucose levels remain normal. Once the pancreas is no longer able to keep up, blood glucose starts to rise, initially after meals, eventually even in the fasting state. Type 2 diabetes is now overt.
Defines insulin resistance and pre-diabetes and describes how they are diagnosed. Lists ways to treat insulin resistance and pre-diabetes to help avoid developing diabetes.
Read about insulin resistance is causes, symptoms, treatment (like diet), risk factors and more. Untreated insulin resistance can lead to type 2 diabetes.
Explains how insulin resistance develops and offers natural symptom relief for women who are insulin resistant.
Insulin resistance syndrome, or metabolic syndrome, increases your risk of diabetes and early heart disease. Find out more.
Insulin resistance is a state in which a given concentration of insulin produces a less-than-expected biological effect.